{"id":434,"date":"2023-09-19T13:00:15","date_gmt":"2023-09-19T13:00:15","guid":{"rendered":"https:\/\/smartfish1.wpengine.com\/?page_id=434"},"modified":"2023-09-28T14:02:43","modified_gmt":"2023-09-28T14:02:43","slug":"cachexia","status":"publish","type":"page","link":"https:\/\/smartfishnutrition.com\/?page_id=434","title":{"rendered":"Cachexia"},"content":{"rendered":"\n
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Cachexia<\/h1>\n<\/div>\n<\/div><\/div>\n\n\n\n
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Cachexia<\/h2>\n\n\n\n

Nutritional management of cachexia with food alone has until now shown little effect. With clinical data indicating that Smartfish formulations could positively influence important underlying mechanisms of cachexia such as insulin resistance, inflammation and anorexia, we decided to invest in developing a product specifically for cachexia, Remune.<\/p>\n\n\n\n

Smartfish medical nutrition products improve the situation for patients with pre-cachexia or cachexia by increasing the uptake of nutrition, hampering the progression of pre-cachexia or cachexia, or alleviating symptoms.<\/p>\n\n\n\n

Remune is a high quality oral nutritional supplement, with carefully selected ingredients to target the underlying mechanisms of cachexia; anorexia, inflammation and insulin resistance1<\/a><\/sup>. The key ingredients of Remune are the marine omega-3 fatty acids, EPA and DHA, vitamin D and whey protein rich in essential amino acids.<\/p>\n\n\n\n

The marine omega-3 fatty acids EPA and DHA has anti-inflammatory properties2<\/a><\/sup> and can positively affect the inflammation associated with cancer and cachexia. EPA and DHA influences muscle protein synthesis3<\/a><\/sup> and a weight-retaining effect has been shown in cancer and cachexia patients4<\/a><\/sup>. This leads to beneficial effects on the weight loss and muscle deterioration associated with cachexia. In cancer-patients, the marine fatty acids have shown anti-tumour properties and beneficial effects on treatment outcome5<\/a><\/sup>.<\/p>\n\n\n\n

Vitamin D deficiency is especially common in medical inpatients6<\/a><\/sup> and people with anorexia7<\/a><\/sup>. Vitamin D is especially important for these patients as it influences the immune-function [16] and plays an important role in muscle function8<\/a><\/sup>. In addition, low levels of vitamin D are associated with insulin resistance9<\/a><\/sup>.<\/p>\n\n\n\n

Protein is essential in promoting muscle growth and preventing muscle-loss10<\/a><\/sup>. Remune contains high-quality whey protein, which is a complete protein as it contains all essential amino acids. Whey protein is easily digestible and therefore leads to less satiety than other protein sources. Whey protein is known for its high content of branched-chain amino acids (BCAA\u2019s), which are especially important in stimulating muscle growth11<\/a><\/sup>.<\/p>\n\n\n\n

In addition, Remune consists of polyphenol-rich juice from fruits and berries, which also contributes with fibre and phytochemicals. Altogether, the composition of Remune is shown to have a low glycemic index below 2112<\/a><\/sup>, and will not impact blood sugar negatively.<\/p>\n\n\n\n

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Relevant studies<\/h3>\n\n\n\n

Below is a list of relevant studies. For a complete list of relevant studies for Smartfish products, visit R&D<\/a>.<\/p>\n<\/div>\n\n\n\n